Hiv/Aids is No Joke. Be Smart, Stay Safe. People living with HIV are increasingly experiencing a range of non-AIDS-related co-morbidities as the population ages, including cardiovascular disease, kidney impairment and bone loss leading to fractures, according to research presented at the IDWeek 2016 meeting in New Orleans in October.
Thanks to effective antiretroviral therapy (ART), more HIV-positive people in the US and Europe are surviving to older ages. Estimates indicate that nearly half of people living with HIV in the US are aged 50 or older. While some research has found that HIV-positive people who were treated promptly with modern ART may have a life expectancy close to that of HIV-negative individuals, those who developed advanced immune deficiency or were treated with suboptimal therapy often have ongoing health problems.
Studies have shown that people with HIV are at higher risk for developing chronic non-AIDS conditions such as heart disease and cancer, and they may do so at younger ages. Some of these conditions have been linked to specific antiretroviral drugs, including kidney impairment and bone loss with tenofovir (Viread) and cardiovascular events with abacavir (Ziagen). HIV patients have multiple non-AIDS-related comorbidities, including risk factors for renal impairment, cardiovascular disease, and fracture/osteoporosis," the researchers concluded. "Among treated HIV patients, the prevalence of comorbidities is increasing over time, especially renal, bone and cardiovascular comorbidities."