#thrombotic

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#thrombotic#Thrombotic#nephrology#medicine#kidneydisease#nephropathy#Thrombocytopenic#BloodSafety#BloodTransfusion#IPEvents#lupusanticoagulant#lupusawareness#fibrin#nephropathology#glomerulus#kidneydiseaseawareness#pathology#histology#histo#microscopic#microscopy#microscope#renalpath#renal#kidney#glom

Hashtags #thrombotic for Instagram

A 49-year-old man presented to the outpatient department with gradually progressive pedal edema and dull aching pain in the right hypochondrium. On examination, physicians found bilateral lower limb pitting pedal edema, mildly enlarged liver, a distended abdomen, and dilated and tortuous superficial veins on the patient’s abdominal wall (A), with a filling pattern from below upward. An echocardiogram showed a dilated inferior vena cava with substantial turbulence at the junction of the inferior vena cava and right atrium. An ascending venogram showing critical narrowing at the suprahepatic segment of the IVC with large collateral (*) (B) suggesting a membranous subtype of Budd–Chiari syndrome. Budd–Chiari syndrome is uncommon (estimated incidence of 0.87 per million population per year), characterized by either thrombotic or nonthrombotic occlusion of hepatic venous outflow. Full details in the CMAJ practice article (subscription required): http://www.cmaj.ca/content/190/22/E689



#meded #medstudent#medschool #medicalschool #medicalstudent #medicine #medical #MD #physician #doctor #doctors #futuredoctor #FOAMed #abdomen #IVC #inferiorvenacava #varices #thrombotic #circulation #budd-chiari


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#Analysis of the #thrombotic & #fibrinolytic activities of #tumor cell–derived extracellular vesicles buff.


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Prof. Zbigniew (Ziggy) Szczepiorkowski talking about #Thrombotic #Thrombocytopenic #Purpura in #AABBME2018
#BloodSafety #BloodTransfusion #IPEvents #PostConference #Highlights
For full interview visit our YouTube Channel!
https://goo.gl/tigyKW


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#Repost @aabbconfme : #Thrombotic #Thrombocytopenic #Purpura will be the subject of Prof. Zbigniew Szczepiorkowski's Lecture in #AABBME2018.
Only few days remaining for the Early Bird Rates so Hurry Up and register today: https://goo.gl/sz5vd2
#ACCME #BloodSafety #BloodTransfusion #IPEvents


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#thrombotic #thrombocytopenic #purpura will be the subject of Prof. Zbigniew Szczepiorkowski's Lecture in #aabbme2018 .
Only few days remaining for the Early Bird Rates so Hurry Up and register today: https://goo.gl/sz5vd2
#ACCME #BloodSafety #BloodTransfusion #IPEvents


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Paroxysmal nocturnal haemoglobinuria (#PNH) is a #thrombotic condition that will paradoxically raise INR and APTT. #Thromboprophylaxis is required....#diagnosis 1)Laboratory findings of hemolysis
•Hemogram: Anaemia ± Leukopoenia ± Thrombocytopenia •Reticulocytosis
•Elevated Indirect Bilirubin Level
•Elevated LDH Level
•Decrease in Haptoglobin Level •Direct Coombs negativity
2)#FlowCytometry Findings Deficiency of GPI anchored proteins (such as #CD55, #CD59)
#Supportive treatment: folic acid, iron replacement and transfusion..#eculuzimab recombinant humanized monoclonal antibody against the complement protein C5#hematology #The_ONLY_Notes_You_Will_Ever_Need #mrcpuk #mrcp#part2 #internalmedicine #doctors #medicaldoctor #medicalstudent #studying #usmle #passmedicine #CME


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Glomerular manifestations of thrombotic microangiopathy, in a transplant patient. PAS stain. Note the presence of fibrin thrombi within glomerular capillary loops, most prominent dead center and at 8-10 o'clock. #pathology #path #kidneydisease #kidneydiseaseawareness #kidney #renal #renalpath #microscope #microscopy #microscopic #histo #histology #glom #glomerulus #nephrology #nephropathy #nephropathology #medicine #thrombotic #fibrin #fibrinthrombi #lupus #lupusawareness #lupusanticoagulant #thrombus


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What are the main therapies for #essentialthrombocythemia ( #ET ), and how do they help? Dr. John Mascarenhas, a #myeloproliferativeneoplasm ( #MPN ) expert at #MountSinai School of Medicine, explains the various treatments currently used for ET. Dr. Mascarenhas discusses the risk of #thrombotic (#bloodclot) episodes that characterize this disease.
http://ow.ly/QPHm303wdOn #mpnsm #cancertreatment #cancerpatient #PowerfulIn2016


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VIDEO: Thrombocythemia (ET) Treatment http://ow.ly/5l6s303xYs0 Mount Sinai NYC Patient Power Europe #Thrombotic #Cancer


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Glomerular manifestations of thrombotic microangiopathy, in the same patient from the previous post. Trichrome stain. The fibrin thrombi are best appreciated at the 5-6:00 position. #pathology #path #kidneydisease #kidneydiseaseawareness #kidney #renal #renalpath #microscope #microscopy #microscopic #histo #histology #glom #glomerulus #nephrology #nephropathy #nephropathology #medicine #lupusanticoagulant #lupusawareness #trichrome #redwhiteandblue #thrombotic #fibrin #thrombus


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Glomerular manifestations of thrombotic microangiopathy, in a transplant patient with lupus anticoagulant. H&E stain. Note the presence of fibrin thrombin within glomerular capillary loops. #pathology #path #kidneydisease #kidneydiseaseawareness #kidney #renal #renalpath #microscope #microscopy #microscopic #histo #histology #glom #glomerulus #nephrology #nephropathy #nephropathology #medicine #thrombotic #fibrin #fibrinthrombi #lupus #lupusawareness #lupusanticoagulant #hande


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Systemic #Lupus #Cerebritis

Findings:
Scattered oval and flame shaped areas of abnormal signal are present in the #subcortical white matter bilaterally, involving the left #frontal lobe, bilateral #occipital lobes, and right #cerebellum. Abnormal signal is evident in the #brainstem as well.

Differential Diagnosis:
The appearance is relatively nonspecific and the differential is broad. Multifocal #ischemic foci are a possibility, due to #vasculitis or venous #thrombosis. This would be an atypical distribution for #MS or #ADEM. #Metastatic disease would not likely have this configuration of lesions.

Discussion:
Up to 7% of patients with #systemic lupus erythematosus develop a #CNS #vasculitis. #Pathologically, there is #perivascular #inflammation and #endothelial cell proliferation. Occipital involvement is characteristic, with sparing of the #periventricular regions. This helps to distinguish the process from #MS. Other manifestations of CNS lupus include atrophy, infarcts, and #hemorrhage. Infarcts in these patients may have several different etiologies, including #thrombotic (#hypercoagulable state), embolic (vegetations), or vasculitic. The vasculitic lesions occasionally respond to #steroids.


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#ishchemic #stroke :
#Ischemic #stroke is the #most common (80%)
and occurs when an artery in the brain is
blocked, either by a narrowing of the #blood
#vessel (arteriosclerosis) or by a #blood #clot.
Ischemic stroke #types :
#Thrombotic stroke :it #occurs when a
blood clot (sthrombus) forms in the
#artery, usually in #areas #narrowed
by #fatty #deposits (atherosclerosis).
Embolic stroke occurs when a clot
or other debris (#embolus) #travels to
the #brain from somewhere else in
the body, and blocks blood flow in
an artery. This is often caused by
abnormal heart rhythm
(heartbeats), such as with atrial
fibrillation, that causes #pooling of
blood in the #heart chambers
and leads to #clot #formation.


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My only happiness, #whitecoats all around! Case study #thrombotic thrombocytopenic purpura


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