Everything will get thrown at you. Other peoples hatred, their jealousy. Your insecurities will jump in your face, your mind will be clouded by self doubt.
Friends will abandon you, lovers will leave you. Your parents will laugh at you. Nature will be ruthless to you, your body will fail you, your emotions will betray.
Never the less you must never ever fucking give up. Ever. You're going to rise past everything. You're always going to strive for the next level.
And when you get there, its all going to start over again until you rise up to the challenge and reach the level even above that.
The game is never ending. Don't you dare lose.